Spironolactone: What It Does and How to Use It

Spironolactone is a medication that blocks a hormone called aldosterone. By doing this, it helps the body get rid of extra salt and water, lowers blood pressure, and reduces hormone‑driven skin problems.

Doctors often prescribe it for high blood pressure, heart failure, and fluid buildup. In dermatology, it’s a go‑to for adult acne and unwanted facial hair because it blocks the effect of male hormones on the skin.

Typical Dosage and How to Take It

For blood pressure, the starting dose is usually 25 mg once a day. Most people end up on 50‑100 mg, split into one or two doses. When it’s used for acne, doctors start with 50 mg daily and may increase to 100‑200 mg depending on skin response.

Take spironolactone with food or a glass of water to avoid stomach upset. If you miss a dose, take it as soon as you remember unless it’s almost time for the next one—don’t double up.

Common Side Effects to Watch

Most side effects are mild. The most frequent ones are:

• Increased urination – you’ll notice you need to pee more often.
• Dizziness, especially when you stand up quickly.
• Breast tenderness or enlargement in both men and women.
• Irregular periods or lighter periods for women.
• Higher potassium levels, which can cause muscle weakness.

Rare but serious reactions include severe allergic rash, trouble breathing, or a fast heartbeat. Seek emergency care if these happen.

Because spironolactone raises potassium, avoid potassium‑rich salts, salty foods, and potassium supplements unless your doctor says it’s ok.

People with kidney disease, liver problems, or a history of low blood pressure should tell their doctor before starting spironolactone. Blood tests are usually done after a few weeks to check potassium and kidney function.

Alcohol can increase dizziness, so keep drinking low while you adjust to the medication.

When using spironolactone for acne, give it at least 2‑3 months before you see clear results. Patience pays off, and your skin will gradually improve as oil production drops.

Finally, store the tablets at room temperature, away from moisture and heat. Keep them out of reach of children.

Spironolactone works well for many people, but it isn’t right for everyone. Talk to your pharmacist or doctor about any other meds you’re taking, especially ACE inhibitors, NSAIDs, or other potassium‑sparing drugs.

With the right dose and regular check‑ups, spironolactone can help manage blood pressure, heart health, and stubborn skin issues safely.